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Organic Pharmaceutical Chemistry

DRUGS and PHARMACEUTICALS

Analgesic Drugs

                An analgesic or pain killer is any member of the group of drugs used to achieve analgesia , relief from pain. The English word for pain is derived form the old French word 'piene' , Latin word 'poene' and Ancient Greek word 'poine'.

Causes Of Pain:

Following can be the reasons for any kind of pain;
  • Stress
  • Tension 
  • Coldness
  • Lack of Oxygen
  • Hotness
  • Carrying heavy loads 

Definition Of Analgesics

            These are the class of compounds which relief the pain without the production of unconsciousness. 
There action may 
  • Peripheral 
  • Central 
  • Peripheral + Central 

Classification On The Basis Of Cause Of Pain 

On the basis of cause of pain the compounds are classified the following two classes 

  1.  True Analgesics: Those compounds which relief the pain may or may not be affecting the cause of pain called True Analgesics.  
  2. False Analgesics : Those compounds which relief the pain by indirect action of reducing or removing the cause of the pain called False Analgesics. 

Classification On The Basis Of Mode Of Action

These compounds are also classified on the basis of mode of action . These are 

  1. Narcotic Analgesic ( Addiction ) Mode of action is Central
  2. Non-Narcotic Analgesics ( Non- Addiction ) Mode of action is Central + Peripheral 

Difference Between Anesthetic and Analgesics 

  • ANESTHETIC produce loss of sensation by blocking the conduction of pain impulse.
  • ANALGESICS decrease the perception of pain impulse , it do not block the pain stimulant.


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